Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5060301 | 0.85 | TDP1 (0.50) | ALDH1A1LMNAKDM4ECA12CA7 | |
| SCHEMBL16672747 | 0.84 | CA12 (0.55) | ALDH1A1LMNAKDM4ECA12CA7 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.78 | TDP1 (0.68) | ALDH1A1LMNAKDM4ECA12CA7 | |
| SCHEMBL4803036 | 0.78 | ABCB1 (0.47) | LMNATDP1ALOX5LTA4HMAPT | |
| SCHEMBL490151 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4ECA12CA7 | |
| SCHEMBL10072108 | 0.77 | TDP1 (0.47) | ALDH1A1LMNACA9TDP1HPGD | |
| Methyl 3-Phenylpropanoate SCHEMBL1893702 | 0.77 | TDP1 (0.66) | ALDH1A1LMNAKDM4ECA12CA7 | |
| Methyl 3-Phenylpropanoate SCHEMBL27447160 | 0.77 | TDP1 (0.66) | ALDH1A1LMNAKDM4ECA12CA7 | |
| Methyl 3-Phenylpropanoate SCHEMBL27315471 | 0.77 | TDP1 (0.66) | ALDH1A1LMNAKDM4ECA12CA7 | |
| SCHEMBL12040756 | 0.76 | TDP1 (0.51) | ALDH1A1LMNATDP1HPGDALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355276-A1 | Ketals and Polyketals as Release Agents | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355276-A1 | Ketals and Polyketals as Release Agents | KARS1, KHK, KLKB1 | ALDH1A1 1358/4885LMNA 3150/4885KDM4E 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.