Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19206667 | 0.96 | LTB4R (0.39) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL19206652 | 0.94 | CDC7 (0.45) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL17407642 | 0.93 | ALKBH3 (0.38) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL2680751 | 0.93 | ABCB1 (0.40) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL19206699 | 0.93 | LTB4R (0.42) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL16154083 | 0.93 | ADORA3 (0.38) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL954143 | 0.92 | LTB4R (0.43) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL20841748 | 0.92 | ALKBH3 (0.41) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL954434 | 0.92 | ABCB1 (0.41) | LTB4RCDC7ALDH1A1KDM4EHTT | |
| SCHEMBL2680919 | 0.91 | ADORA3 (0.38) | LTB4RCDC7ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612411-B1 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | INSTITUT PASTEUR (FR) | 2026-04-28 | — | — | US | disclosed |
| US-12606863-B2 | Bioluminescent detection of DNA synthesis | PROMEGA CORPORATION (US) | 2026-04-21 | — | — | US | disclosed |
| US-12576164-B2 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | INSTITUT PASTEUR (FR) | 2026-03-17 | — | — | US | disclosed |
| EP-4073512-B1 | COMPOSITIONS AND METHODS FOR BIOLUMINESCENT DETECTION USING MULTIFUNCTIONAL PROBES | PROMEGA CORP (US) | 2025-11-12 | — | — | EP | disclosed |
| US-12422369-B2 | Immunosensor | PPB Technology Pty Ltd (AU) | 2025-09-23 | — | — | US | disclosed |
| US-20250264464-A1 | COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING BIOLUMINESCENCE | PROMEGA CORPORATION | 2025-08-21 | — | — | US | disclosed |
| CN-119955899-A | Compositions, methods and kits for stabilizing coelenterazine and analogs and derivatives thereof | 普洛麦格公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-112996923-B | Compositions and methods for stabilizing coelenterazine and analogs and derivatives thereof | 普洛麦格公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024217577-A1 | PEPTIDE AND LUMINESCENT COMPLEX CONTAINING SAME | 深圳琅技生命科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| EP-3964501-B1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | PASTEUR INSTITUT (FR) | 2024-09-04 | — | — | EP | disclosed |
| EP-1894933-A2 | Compositions, methods and kits pertaining to luminescent compounds | PROMEGA CORPORATION (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20080050760-A1 | COMPOSITIONS AND METHODS TO CO-LOCALIZE LUMINOPHORES WITH LUMINESCENT PROTEINS | PROMEGA CORPORATION | 2008-02-28 | — | — | US | disclosed |
| US-20080050760-A1 | COMPOSITIONS AND METHODS TO CO-LOCALIZE LUMINOPHORES WITH LUMINESCENT PROTEINS | PROMEGA CORPORATION | 2008-02-28 | — | — | US | disclosed |
| US-7268229-B2 | Compounds to co-localize luminophores with luminescent proteins | PROMEGA CORPORATION (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268229-B2 | Compounds to co-localize luminophores with luminescent proteins | PROMEGA CORPORATION (US) | 2007-09-11 | — | — | US | disclosed |
| EP-1546162-A4 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY | PROMEGA CORP (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-1546162-A2 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY | PROMEGA CORPORATION (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20040224377-A1 | Compositions and methods to quench light from optical reactions | PROMEGA CORPORATION | 2004-11-11 | — | — | US | disclosed |
| US-20040171099-A1 | Using luciferin derivatives for analyzing metabolic activity in animals, cells or in cell-free reaction formulations | PROMEGA CORPORATION | 2004-09-02 | — | — | US | disclosed |
| WO-2004027378-A2 | LUMINESCENCE-BASED METHODS AND PROBES FOR MEASURING CYTOCHROME P450 ACTIVITY | PROMEGA CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606863-B2 | Bioluminescent detection of DNA synthesis | PCNA, MKI67, POLL | LTB4R 2800/4885CDC7 513/4885ALDH1A1 946/4885 |
| US-12576164-B2 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | LUC7L2, HLCS, LANCL1 | LTB4R 93/4885CDC7 1284/4885ALDH1A1 659/4885 |
| US-12612411-B1 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | LUC7L2, MRPL21, CRY1 | LTB4R 1256/4885CDC7 2019/4885ALDH1A1 1484/4885 |
| US-12422369-B2 | Immunosensor | KLK3, CD47, FCGR3B | LTB4R 2264/4885CDC7 4555/4885ALDH1A1 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.