SCHEMBL7790782

SCHEMBL7790782

[c]1nc2ccccc2c2cc3ccccc3cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
NQO2 P16083 2/20 0.41
KDM4E B2RXH2 4/20 0.41
GPR3 P46089 3/20 0.41
ALDH1A1 P00352 4/20 0.38
GLA P06280 4/20 0.38
HPGD P15428 3/20 0.38
ACHE P22303 3/20 0.38
MAPT P10636 2/20 0.38
HSD17B10 Q99714 2/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
CLK1 P49759 1/20 0.37
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
PTBP1 P26599 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24030 0.79 GPR3 (0.46) NQO2KDM4EGPR3ALDH1A1GLA
SCHEMBL27656095 0.77 GPR3 (0.44) NQO2KDM4EGPR3ALDH1A1GLA
SCHEMBL655508 0.73 HSD17B10 (0.39) NQO2KDM4EGPR3ALDH1A1GLA
SCHEMBL4506468 0.70 ESR1 (0.68) ESR1ESR2NQO2KDM4EGPR3
SCHEMBL15578212 0.69 KDM4E (0.39) KDM4EGPR3ALDH1A1HPGDACHE
SCHEMBL15578037 0.69 ACHE (0.39) KDM4EGPR3ALDH1A1HPGDACHE
SCHEMBL5478388 0.68 GPR3 (0.64) ESR1ESR2NQO2KDM4EGPR3
SCHEMBL17063434 0.68 ALDH1A1 (0.41) ESR1ESR2NQO2KDM4EALDH1A1
SCHEMBL2514493 0.68 GPR3 (0.34) KDM4EGPR3ALDH1A1GLAHPGD
SCHEMBL2518791 0.68 KDM4E (0.46) KDM4EGPR3ALDH1A1MAPTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed