SCHEMBL2403145

SCHEMBL2403145

Oc1ccc(-c2ccc(O)c(F)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.70
ESR2 Q92731 10/20 0.70
HSD17B1 P14061 3/20 0.70
HSD17B2 P37059 3/20 0.70
ALOX5 P09917 1/20 0.62
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
HSD17B10 Q99714 1/20 0.62
KIF11 P52732 1/20 0.59
CYP17A1 P05093 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP19A1 P11511 1/20 0.55
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
MGLL Q99685 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895567 1.00 ESR1 (0.70) ESR1ESR2HSD17B1HSD17B2ALOX5
SCHEMBL30635318 0.90 ESR1 (0.68) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL857363 0.90 ESR1 (0.68) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL9221458 0.86 HSD17B1 (0.64) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL31549497 0.84 HSD17B1 (0.74) ESR1ESR2HSD17B1HSD17B2ALOX5
SCHEMBL8477872 0.84 HSD17B1 (0.74) ESR1ESR2HSD17B1HSD17B2ALOX5
SCHEMBL1513602 0.83 KIF11 (0.61) ESR1ESR2HSD17B1HSD17B2ALOX5
SCHEMBL21199950 0.83 ESR1 (0.61) ESR1ESR2HSD17B1HSD17B2KDM4E
SCHEMBL3924993 0.83 ESR1 (1.00) ESR1ESR2HSD17B1HSD17B2
SCHEMBL12012444 0.82 HSD17B1 (0.60) ESR1ESR2HSD17B1HSD17B2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114987024-B Composite board mobile phone cover with textures and production process thereof 惠州市纵胜电子材料有限公司 2023-10-03 CN disclosed
CN-114987024-A Composite wrench cover with textures and production process thereof 惠州市纵胜电子材料有限公司 2022-09-02 CN disclosed
US-11066602-B2 Reactive mesogen and liquid crystal composition including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-20 US disclosed
CN-109517316-B Fluorine-containing active ester, preparation method thereof and resin cured product containing fluorine-containing active ester 广东莱尔新材料科技股份有限公司 2021-05-04 CN disclosed
EP-3725764-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2020-10-21 EP disclosed
US-20200299578-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-09-24 US disclosed
CN-108485683-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 中节能万润股份有限公司 2020-04-28 CN disclosed
WO-2019188920-A1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT JNC株式会社 2019-10-03 WO disclosed
US-20190276741-A1 REACTIVE MESOGEN AND LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-12 US disclosed
US-10344213-B2 Reactive mesogen and liquid crystal composition including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-09 US disclosed
US-8017199-B2 Cellulose acylate film, process for producing cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-7655643-B2 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2010-02-02 US disclosed
US-7655643-B2 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2010-02-02 US disclosed
US-7462306-B2 Cellulose acylate film, process for producing cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-12-09 US disclosed
CN-101225026-A Fluoro-4, 4' -biphenol bis allyl ether and synthetic method thereof YANTAI VALIANT FINE CHEMICALS (CN) 2008-07-23 CN disclosed
US-20070298194-A1 Cellulose Acylate Film, Process for Producing Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-20070099885-A1 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2007-05-03 US disclosed
US-20070099885-A1 Antibacterial macrocycles with substituted biphenyl AICURIS GMBH & CO. KG (DE) 2007-05-03 US disclosed
WO-2006064967-A1 CELLULOSE ACYLATE FILM, PROCESS FOR PRODUCING CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-06-22 WO disclosed
US-20060093759-A1 Cellulose acylate film, process for producing cellulose acylate film, polarizing plate and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11066602-B2 Reactive mesogen and liquid crystal composition including the same SPIN2B, ZYX, ZP1 ESR1 900/4885ESR2 1127/4885HSD17B1 2816/4885
US-20070099885-A1 Antibacterial macrocycles with substituted biphenyl NOD2, AHR, BCL2 ESR1 347/4885ESR2 163/4885HSD17B1 2496/4885
US-10344213-B2 Reactive mesogen and liquid crystal composition including the same SCO2, CCNL2, CCNB2 ESR1 663/4885ESR2 479/4885HSD17B1 2973/4885
US-20200299578-A1 POLYMERIZABLE COMPOUND HAVING METHOXYMETHYL ACRYLIC GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, CCND1, CPNE4 ESR1 216/4885ESR2 1627/4885HSD17B1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.