Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102011 | 0.80 | NCF1 (0.48) | LMNA | |
| SCHEMBL102140 | 0.78 | HRH3 (0.45) | LMNA | |
| SCHEMBL1678779 | 0.78 | — | — | |
| SCHEMBL18948428 | 0.77 | OPRK1 (0.32) | — | |
| SCHEMBL22388201 | 0.77 | HRH3 (0.37) | — | |
| SCHEMBL25915237 | 0.77 | HTT (0.32) | — | |
| SCHEMBL23695997 | 0.77 | PIK3CD (0.44) | LMNA | |
| SCHEMBL23105099 | 0.77 | ARG1 (0.40) | LMNA | |
| SCHEMBL102108 | 0.77 | HRH3 (0.41) | LMNA | |
| SCHEMBL25133391 | 0.76 | NCF1 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231927-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS WITH A TRICYCLIC CEREBLON LIGAND | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-11-18 | — | — | WO | disclosed |