SCHEMBL24034152

SCHEMBL24034152

CC(O)c1nnn(C(c2ccccc2)(c2ccccc2)c2ccccc2)n1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RECQL P46063 1/20 0.32
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10077140 0.84 CYP1A2 (0.34) CYP1A2CYP2D6CYP11B1CYP11B2
Oxalic Acid SCHEMBL2438368 0.81 CYP1A2 (0.40) CYP1A2CYP2D6POLBSMN1; SMN2
SCHEMBL22615889 0.79 KDM4E (0.31) CYP1A2CYP2D6
SCHEMBL24034153 0.77 POLB (0.32) POLBSMN1; SMN2
SCHEMBL24034155 0.77 POLB (0.39) CYP1A2CYP2D6POLBSMN1; SMN2
SCHEMBL5603982 0.76 CYP11B1 (0.30) CYP11B1CYP11B2
SCHEMBL761956 0.74 CYP11B1 (0.35) POLBSMN1; SMN2CYP11B1CYP11B2
SCHEMBL9255395 0.74 NPC1 (0.33) POLBSMN1; SMN2
SCHEMBL30343506 0.74 POLB (0.39) CYP1A2CYP2D6POLBSMN1; SMN2
SCHEMBL9315829 0.73 AGTR1 (0.42) CYP1A2POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. 2023-09-21 US disclosed
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. 2023-09-21 US disclosed
CN-116261561-A Certain chemical compositions and methods of use thereof 奧基生物技术有限公司 2023-06-13 CN disclosed
US-11591322-B2 Certain chemical compositions and methods of use thereof ALGEN BIOTECHNOLOGIES, INC. (US) 2023-02-28 US disclosed
WO-2021231892-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF ALGEN BIOTECHNOLOGIES, INC. (US) 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591322-B2 Certain chemical compositions and methods of use thereof CDK9, CDK19, CDK6 CYP1A2 2760/4885CYP2D6 2719/4885POLB 612/4885
US-20230295135-A1 CERTAIN CHEMICAL COMPOSITIONS AND METHODS OF USE THEREOF CDK9, CDK19, CDK6 CYP1A2 2760/4885CYP2D6 2719/4885POLB 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.