Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.46 |
| ▸ | APLNR | P35414 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988486 | 0.83 | AKR1B1 (0.39) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL22990154 | 0.77 | CA12 (0.32) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL21556044 | 0.75 | CA2 (0.61) | CA12CA1CA2CA4CA6 | |
| SCHEMBL13266077 | 0.75 | CA12 (0.36) | CA12CA1CA2CA4CA6 | |
| SCHEMBL21627142 | 0.75 | ALDH1A1 (0.52) | KMT2APKMKDM4ELMNAMAPT | |
| SCHEMBL29397251 | 0.72 | CA12 (0.62) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL10834173 | 0.72 | AGTR1 (0.65) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL25356808 | 0.67 | HTR2A (0.62) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL20379895 | 0.67 | KMT2A (0.56) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 | |
| SCHEMBL3158170 | 0.67 | HTR2A (0.62) | HTR2AKCNH2AGTR1HSP90AA1CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355378-A9 | HETEROCYCLIC COMPOUNDS EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) AND THEIR USE IN ELECTROLUMINESCENT DEVICES | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355378-A9 | HETEROCYCLIC COMPOUNDS EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) AND THEIR USE IN ELECTROLUMINESCENT DEVICES | ETFA, TEAD2, TERF2 | HTR2A 618/4885KCNH2 569/4885AGTR1 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.