Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24031256 | 0.87 | PRMT3 (0.30) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL16297669 | 0.86 | PRMT3 (0.40) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL24033160 | 0.85 | CA12 (0.38) | — | |
| SCHEMBL260446 | 0.85 | ALDH1A1 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL14445500 | 0.85 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL1644155 | 0.83 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL14271348 | 0.83 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL14271349 | 0.82 | — | — | |
| SCHEMBL10123339 | 0.82 | PRMT3 (0.37) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL12933032 | 0.81 | ALDH1A1 (0.35) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231679-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF GAP JUNCTION PROTEIN BETA 2 (GJB2) | KORRO BIO, INC. (US) | 2021-11-18 | — | — | WO | disclosed |