Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128720 | 0.90 | MEN1 (0.32) | — | |
| SCHEMBL13500395 | 0.90 | MEN1 (0.32) | — | |
| SCHEMBL6123945 | 0.89 | KDM4A (0.36) | ALDH1A1TDP1KDM4AKDM4C | |
| SCHEMBL27003670 | 0.86 | PRMT3 (0.40) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL12933032 | 0.85 | ALDH1A1 (0.35) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL24036624 | 0.85 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL14445500 | 0.85 | PRMT3 (0.33) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL26652081 | 0.84 | — | — | |
| SCHEMBL6123949 | 0.83 | PAOX (0.34) | ALDH1A1TDP1PRMT3CARM1PRMT6 | |
| SCHEMBL1644155 | 0.83 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295614-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF ARGININOSUCCINATE LYASE (ASL) | KORRO BIO, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20230190968-A1 | ANTI-CD38 SINGLE-DOMAIN ANTIBODIES IN DISEASE MONITORING AND TREATMENT | Université de Liège (BE) | 2023-06-22 | — | — | US | disclosed |
| US-20230174989-A1 | Methods and Compositions for the ADAR-Mediated Editing of ABCA4 | KORRO BIO, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-9975870-B2 | 5,6-dimethoxy-1,1-dioxobenzo[b]thiophene-2-methyloxycarbonyl (DM-Bsmoc) and related amino-protecting groups | MASSACHUSETTS, UNIVERSITY OF (US) | 2018-05-22 | — | — | US | disclosed |
| US-20170183655-A1 | COMPOSITIONS AND USES FOR TREATMENT THEREOF | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2017-06-29 | — | — | US | disclosed |
| US-20170073748-A1 | METHODS AND COMPOSITIONS FOR GENOMIC TARGET ENRICHMENT AND SELECTIVE DNA SEQUENCING | PetaOmics, Inc. | 2017-03-16 | — | — | US | disclosed |
| US-20170002355-A1 | cGAP-PNA MULTIVALENT PEPTIDE NUCLEIC ACID LIGAND DISPLAY | THE USA, AS REPRESENTED BY THE SECRETARY, DEPART- MENT OF HEALTH AND HUMAN SERVICES (US) | 2017-01-05 | — | — | US | disclosed |
| US-20160152591-A1 | THE 5,6-DIMETHOXY-1,1-DIOXOBENZO[B]THIOPHENE-2-METHYLOXYCARBONYL (DM-BSMOC) AND RELATED AMINO-PROTECTING GROUPS | MASSACHUSETTS, UNIVERSITY OF | 2016-06-02 | — | — | US | disclosed |
| US-9156778-B2 | Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-10-13 | — | — | US | disclosed |
| US-20140148500-A1 | PROGRAMMABLE SELF-ASSEMBLED NANOSTRUCTURES BASED ON SIDECHAIN-MODIFIED PNA FOR THE MULTIVALENT DISPLAY OF LIGANDS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2014-05-29 | — | — | US | disclosed |
| US-8450469-B2 | Synthesis of peptide nucleic acids conjugated with amino acids and their application | PANAGENE INC. (KR) | 2013-05-28 | — | — | US | disclosed |
| US-20120322053-A1 | CROSS-COUPLED PEPTIDE NUCLEIC ACIDS FOR DETECTION OF NUCLEIC ACIDS OF PATHOGENS | APPELLA DANIEL H (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120107794-A1 | Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2012-05-03 | — | — | US | disclosed |
| US-8133985-B2 | Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same | PANAGENE INC. (KR) | 2012-03-13 | — | — | US | disclosed |
| US-20110014715-A1 | Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application | PANAGENE INC. (KR) | 2011-01-20 | — | — | US | disclosed |
| US-7642057-B2 | Method and probes for the detection of chromosome aberrations | DAKO DENMARK A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20090312197-A1 | PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME | PANAGENE INC. (KR) | 2009-12-17 | — | — | US | disclosed |
| US-20080187934-A1 | Using peptide nucleic acid probes to detect chromosome aberrations in eukaryotic cells | DAKO A/S (DK) | 2008-08-07 | — | — | US | disclosed |
| US-7368245-B2 | Method and probes for the detection of chromosome aberrations | DAKO DENMARK A/S (DK) | 2008-05-06 | — | — | US | disclosed |
| US-20070172842-A1 | Methods for isolating and identifying novel target-specific structuremers for use in the biological sciences | BRAUN ANDREAS | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312197-A1 | PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME | NPPA, PARN, PARG | ALDH1A1 3477/4885TDP1 230/4885PRMT3 535/4885 |
| US-20230190968-A1 | ANTI-CD38 SINGLE-DOMAIN ANTIBODIES IN DISEASE MONITORING AND TREATMENT | CD38, CD22, CD2 | ALDH1A1 681/4885TDP1 837/4885PRMT3 3007/4885 |
| US-20170002355-A1 | cGAP-PNA MULTIVALENT PEPTIDE NUCLEIC ACID LIGAND DISPLAY | CGAS, STING1, IAPP | ALDH1A1 4744/4885TDP1 56/4885PRMT3 2443/4885 |
| US-20140148500-A1 | PROGRAMMABLE SELF-ASSEMBLED NANOSTRUCTURES BASED ON SIDECHAIN-MODIFIED PNA FOR THE MULTIVALENT DISPLAY OF LIGANDS | NCL, PARN, COIL | ALDH1A1 4738/4885TDP1 662/4885PRMT3 2473/4885 |
| US-20230174989-A1 | Methods and Compositions for the ADAR-Mediated Editing of ABCA4 | ADAR, ABCB4, ADA | ALDH1A1 391/4885TDP1 60/4885PRMT3 3957/4885 |
| US-20230295614-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF ARGININOSUCCINATE LYASE (ASL) | ADAR, ADA, ASS1 | ALDH1A1 725/4885TDP1 64/4885PRMT3 313/4885 |
| US-20160152591-A1 | THE 5,6-DIMETHOXY-1,1-DIOXOBENZO[B]THIOPHENE-2-METHYLOXYCARBONYL (DM-BSMOC) AND RELATED AMINO-PROTECTING GROUPS | DAO, DDC, PTMS | ALDH1A1 4651/4885TDP1 1834/4885PRMT3 178/4885 |
| US-20110014715-A1 | Synthesis of Peptide Nucleic Acids Conjugated with Amino Acids and Their Application | CPSF6, RNGTT, DNPEP | ALDH1A1 4448/4885TDP1 2021/4885PRMT3 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.