SCHEMBL10123339

SCHEMBL10123339

CNCCN(CC(C)=O)C(C)=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.37
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
PRMT1 Q99873 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
KDM4A O75164 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14445500 0.82 PRMT3 (0.33) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL260446 0.82 ALDH1A1 (0.33) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL24036624 0.82 PRMT3 (0.33) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL14271348 0.80 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL15907847 0.80 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1644155 0.80 PRMT3 (0.32) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1832441 0.80 PRMT3 (0.39) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL12933032 0.79 ALDH1A1 (0.35) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1834034 0.78 CA12 (0.41) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL1831672 0.78 PRMT3 (0.37) PRMT3CARM1PRMT6PRMT1PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022261030-A1 OLIGONUCLEOTIDE ANALOGUE MODULATORS OF ONCOGENES NEUBASE THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
WO-2022261029-A2 PEPTIDE NUCLEIC ACID THERAPEUTICS FOR TRINUCLEOTIDE REPEAT DISORDERS NEUBASE THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
WO-2022132194-A2 OLIGONUCLEOTIDE ANALOGUE THERAPEUTICS FOR TREATMENT OF NEUROMUSCULAR DISEASE NEUBASE THERAPEUTICS, INC. (US) 2022-06-23 WO disclosed
US-20120115136-A1 PNA DIAGNOSTIC USE PNA Patent Owners (a/k/a CIG) (US) 2012-05-10 US disclosed
US-20120115136-A1 PNA DIAGNOSTIC USE PNA Patent Owners (a/k/a CIG) (US) 2012-05-10 US disclosed
US-7378485-B2 Peptide nucleic acids with polyamide-containing backbones BUCHARDT OLE 2008-05-27 US disclosed
US-7378485-B2 Peptide nucleic acids with polyamide-containing backbones BUCHARDT OLE 2008-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120115136-A1 PNA DIAGNOSTIC USE RNASE1, NCL, PABPC4 PRMT3 2262/4885CARM1 2819/4885PRMT6 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.