SCHEMBL24038544

SCHEMBL24038544

O=C(CCC(=O)NCCOCCOCCNC(=O)OCc1ccccc1)NCCCC[C@H](NC(=O)CCC(=O)NCCOCCOCCNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.66
LMNA P02545 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MMP2 P08253 3/20 0.55
MMP9 P14780 3/20 0.55
SIRT2 Q8IXJ6 1/20 0.55
SIRT1 Q96EB6 1/20 0.55
CPB1 P15086 1/20 0.54
CPB2 Q96IY4 1/20 0.54
MMP1 P03956 1/20 0.53
MMP3 P08254 1/20 0.53
MMP7 P09237 1/20 0.53
MMP13 P45452 1/20 0.53
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24038542 1.00 FOLH1 (0.66) FOLH1LMNASMN1; SMN2MMP2MMP9
SCHEMBL25597725 0.92 LMNA (0.57) FOLH1LMNASMN1; SMN2SIRT2SIRT1
SCHEMBL25260928 0.90 FOLH1 (0.59) FOLH1LMNASMN1; SMN2SIRT2CPB1
SCHEMBL24038748 0.89 KLK7 (0.55) FOLH1LMNASMN1; SMN2
SCHEMBL29214548 0.89 KLK7 (0.55) FOLH1LMNASMN1; SMN2
SCHEMBL29072085 0.88 FOLH1 (0.76) FOLH1MMP2MMP9SIRT2SIRT1
SCHEMBL29072081 0.88 FOLH1 (0.76) FOLH1MMP2MMP9SIRT2SIRT1
SCHEMBL30823334 0.88 FOLH1 (0.64) FOLH1LMNASMN1; SMN2MMP2MMP9
SCHEMBL23451327 0.87 FOLH1 (0.57) FOLH1LMNASMN1; SMN2SIRT2SIRT1
SCHEMBL23451328 0.87 FOLH1 (0.57) FOLH1LMNASMN1; SMN2SIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115516044-B Fluorescent dimer compounds useful as probes for detection of endogenous receptors 斯特拉斯堡大学 2024-05-14 CN disclosed
US-20230174480-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS UNIVERSITE DE STRASBOURG (FR) 2023-06-08 US disclosed
US-20230174480-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS UNIVERSITE DE STRASBOURG (FR) 2023-06-08 US disclosed
EP-4150009-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS Université de Strasbourg (FR) 2023-03-22 EP disclosed
WO-2021228939-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS UNIVERSITE DE STRASBOURG (FR) 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174480-A1 FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS GPR3, GPR174, GPR139 FOLH1 554/4885LMNA 4464/4885SMN1; SMN2 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.