Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22262822 | 1.00 | HPGD (0.42) | HPGDKDM4ENLRP3SLC6A3SLC6A2 | |
| SCHEMBL22262939 | 0.93 | KDM4E (0.46) | HPGDKDM4ENLRP3SLC6A3ADRA1D | |
| SCHEMBL22263002 | 0.90 | SLC6A3 (0.41) | KDM4ENLRP3SLC6A3SLC6A2MAPT | |
| SCHEMBL22262936 | 0.85 | SLC6A3 (0.38) | SLC6A3SLC6A2 | |
| SCHEMBL24039084 | 0.84 | ALDH1A1 (0.44) | HPGDKDM4ESLC6A3SLC6A2ADRA1D | |
| SCHEMBL22263029 | 0.84 | ALDH1A1 (0.44) | HPGDKDM4ESLC6A3SLC6A2ADRA1D | |
| SCHEMBL24039098 | 0.83 | SLC6A3 (0.38) | SLC6A3SLC6A2SIGMAR1HTR2AHRH1 | |
| SCHEMBL22262731 | 0.83 | SLC6A3 (0.38) | SLC6A3SLC6A2SIGMAR1HTR2AHRH1 | |
| SCHEMBL20876028 | 0.83 | SLC6A3 (0.38) | SLC6A3SLC6A2SIGMAR1HTR2AHRH1 | |
| SCHEMBL20876088 | 0.82 | CYP2C19 (0.40) | KDM4ESLC6A3SLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180479-B2 | Antiviral compounds | HAPLOGEN GMBH (AT) | 2021-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180479-B2 | Antiviral compounds | PLA2G1B, PLA2G4A, PLA2G4C | HPGD 1345/4885KDM4E 3704/4885NLRP3 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.