Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736919 | 0.91 | MEN1 (0.40) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL883393 | 0.88 | DHFR (0.41) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL30457667 | 0.85 | DHFR (0.45) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL5702491 | 0.85 | MEN1 (0.40) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL11770956 | 0.85 | ALDH1A1 (0.41) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL4381658 | 0.84 | DHFR (0.45) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL28455748 | 0.84 | KDM4C (0.51) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL3500438 | 0.83 | TNK2 (0.44) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL28981248 | 0.82 | CALM1 (0.41) | DHFRMEN1KMT2AKDM4CTNK2 | |
| SCHEMBL30279565 | 0.82 | CALM1 (0.41) | DHFRMEN1KMT2AKDM4CTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194439-B | SOCE inhibitors and therapeutic uses thereof | 国家医疗保健研究所 | 2025-04-08 | — | — | CN | disclosed |
| CN-116194439-A | SOCE inhibitors and therapeutic uses thereof | 国家医疗保健研究所 | 2023-05-30 | — | — | CN | disclosed |
| EP-4157822-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021233994-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2021-11-25 | — | — | WO | disclosed |
| EP-3912972-A1 | SOCE INHIBITORS AND THERAPEUTIC USES THEREOF | Centre Hospitalier Régional et Universitaire de Brest (FR) | 2021-11-24 | — | — | EP | disclosed |