Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046874 | 0.85 | CSNK2A2 (0.46) | CYP1A1CYP1B1CYP1A2ALDH1A1HPGD | |
| SCHEMBL24046884 | 0.83 | LOXL2 (0.42) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL24046887 | 0.79 | LOXL2 (0.41) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL24046879 | 0.73 | LOXL2 (0.44) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL24046885 | 0.72 | ALDH1A1 (0.44) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL24046878 | 0.72 | CYP3A4 (0.43) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL21822771 | 0.71 | CYP3A4 (0.67) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL311288 | 0.69 | LOXL2 (0.47) | LOXL2CYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL21822612 | 0.68 | CYP3A4 (0.49) | LOXL2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL24046883 | 0.68 | CSNK2A2 (0.51) | CYP1A1CYP1B1CYP1A2CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |