Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046879 | 0.86 | LOXL2 (0.44) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046885 | 0.85 | ALDH1A1 (0.44) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046876 | 0.85 | CSNK2A2 (0.54) | CYP3A4CYP2C19TSHRALDH1A1HPGD | |
| SCHEMBL24046887 | 0.82 | LOXL2 (0.41) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL21822771 | 0.77 | CYP3A4 (0.67) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046884 | 0.75 | LOXL2 (0.42) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046881 | 0.72 | LOXL2 (0.40) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046880 | 0.72 | CSNK2A2 (0.55) | CYP3A4CYP2C19ALDH1A1HPGDMEN1 | |
| SCHEMBL21822612 | 0.71 | CYP3A4 (0.49) | CYP3A4CYP2C19TSHRLOXL2ALDH1A1 | |
| SCHEMBL24046882 | 0.71 | CSNK2A2 (0.54) | CYP3A4ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |