Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046878 | 0.86 | CYP3A4 (0.43) | LOXL2MCL1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL24046885 | 0.86 | ALDH1A1 (0.44) | LOXL2MCL1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL24046880 | 0.85 | CSNK2A2 (0.55) | MCL1CYSLTR2CYSLTR1CYP3A4ALDH1A1 | |
| SCHEMBL24046887 | 0.83 | LOXL2 (0.41) | LOXL2MCL1CYSLTR2CYSLTR1CYP3A4 | |
| SCHEMBL24046884 | 0.76 | LOXL2 (0.42) | LOXL2MCL1CYP3A4ALDH1A1HPGD | |
| SCHEMBL21822771 | 0.75 | CYP3A4 (0.67) | LOXL2CYP3A4ALDH1A1HPGDCYP2C19 | |
| SCHEMBL24046881 | 0.73 | LOXL2 (0.40) | LOXL2MCL1CYP3A4ALDH1A1HPGD | |
| SCHEMBL21822612 | 0.72 | CYP3A4 (0.49) | LOXL2CYP3A4ALDH1A1HPGDCYP2C19 | |
| SCHEMBL24046882 | 0.72 | CSNK2A2 (0.54) | CYSLTR2CYSLTR1CYP3A4ALDH1A1HPGD | |
| SCHEMBL24046876 | 0.72 | CSNK2A2 (0.54) | CYSLTR2CYSLTR1CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |