Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046787 | 0.88 | CSNK2A2 (0.53) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| SCHEMBL24046794 | 0.82 | MAOB (0.63) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| Methoxyvone SCHEMBL29373562 | 0.75 | CYP3A4 (1.00) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| Methoxyvone SCHEMBL3409370 | 0.75 | CYP3A4 (1.00) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| SCHEMBL24046780 | 0.75 | ABCB1 (0.65) | MAPTCYP3A4PLGABCB1CSNK2A2 | |
| SCHEMBL24046902 | 0.73 | TNKS (0.64) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| SCHEMBL24047003 | 0.72 | ABCB1 (0.61) | MAPTCYP3A4TP53SMN1; SMN2PLG | |
| SCHEMBL20664412 | 0.71 | ADORA3 (0.76) | MAPTCYP3A4TP53SMN1; SMN2ABCB1 | |
| SCHEMBL24046933 | 0.70 | ABCB1 (0.76) | MAPTCYP3A4SMN1; SMN2ABCB1MAOB | |
| SCHEMBL20868304 | 0.69 | MAPT (0.79) | MAPTCYP3A4TP53SMN1; SMN2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |