Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24047002 | 0.88 | MAPT (0.59) | CSNK2A2CSNK2BCSNK2A1ADORA3POLB | |
| SCHEMBL13479744 | 0.77 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1ADORA3POLB | |
| SCHEMBL24046902 | 0.76 | TNKS (0.64) | ADORA3POLBKMT2AALDH1A1TDP1 | |
| SCHEMBL24046794 | 0.74 | MAOB (0.63) | CSNK2A2CSNK2BCSNK2A1KMT2AALDH1A1 | |
| SCHEMBL28568538 | 0.73 | CYP3A4 (0.72) | CSNK2A2CSNK2BCSNK2A1ADORA3KMT2A | |
| SCHEMBL20664412 | 0.71 | ADORA3 (0.76) | CSNK2A2CSNK2BCSNK2A1ADORA3POLB | |
| SCHEMBL28914421 | 0.70 | GABRP (0.57) | CSNK2A2CSNK2BCSNK2A1ADORA3ALDH1A1 | |
| SCHEMBL28588026 | 0.68 | CYP3A4 (0.62) | CSNK2A2CSNK2BCSNK2A1ADORA3KMT2A | |
| SCHEMBL28576015 | 0.68 | CSNK2A2 (0.53) | CSNK2A2CSNK2BCSNK2A1ADORA3KMT2A | |
| SCHEMBL13598259 | 0.67 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1ADORA3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |