Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183007 | 0.73 | — | — | |
| SCHEMBL43992 | 0.72 | — | — | |
| SCHEMBL11578150 | 0.71 | PTPN1 (0.36) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL5280889 | 0.71 | — | — | |
| SCHEMBL5889497 | 0.70 | SENP1 (0.47) | — | |
| SCHEMBL26103828 | 0.70 | MAPT (0.46) | LMNA | |
| SCHEMBL16322420 | 0.69 | MAPK1 (0.38) | LMNA | |
| SCHEMBL8838122 | 0.68 | ALDH1A1 (0.39) | PTPN1CHRM3LMNACHRM2CHRM4 | |
| SCHEMBL43932 | 0.68 | — | — | |
| SCHEMBL1481724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8795647-B2 | Alternating ring-opening metathesis polymerization | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-08-05 | — | — | US | disclosed |
| US-20110212046-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2010022284-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212046-A1 | ALTERNATING RING-OPENING METATHESIS POLYMERIZATION | PARG, PIN1, PARP4 | PTPN1 4406/4885CHRM3 4145/4885LMNA 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.