Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15107096 | 0.84 | TP53 (0.41) | KDM4EMAPTALOX15FABP3FABP4 | |
| SCHEMBL2406933 | 0.83 | KDM4E (0.43) | KDM4EMAPTFABP3FABP4ALDH1A1 | |
| SCHEMBL19992813 | 0.80 | KDM4E (0.66) | KDM4EMAPTALOX15DAOMEN1 | |
| SCHEMBL14072938 | 0.80 | DAO (0.59) | KDM4EMAPTALOX15FABP3FABP4 | |
| SCHEMBL23511677 | 0.78 | KDM4E (0.50) | KDM4EMAPTALOX15DAOMEN1 | |
| SCHEMBL26651097 | 0.75 | HDAC4 (0.42) | ALDH1A1 | |
| SCHEMBL26651104 | 0.75 | PRKAB2 (0.38) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL12272917 | 0.74 | FABP3 (0.42) | KDM4EMAPTALOX15FABP3FABP4 | |
| SCHEMBL2411219 | 0.74 | RARA (0.44) | MAPTFABP3FABP4MEN1KMT2A | |
| SCHEMBL22858991 | 0.73 | ALDH1A1 (0.45) | MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8722730-B2 | 5-membered heterocyclic compound | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-05-13 | — | — | US | disclosed |
| CN-101821236-B | Five-membered heterocyclic compound | RES FOUND ITSUU LAB | 2013-05-08 | — | — | CN | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2011-09-01 | — | — | US | disclosed |
| CN-101560272-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-04-13 | — | — | CN | disclosed |
| CN-101560273-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-03-23 | — | — | CN | disclosed |
| CN-101821236-A | Five-membered heterocyclic compound | RES FOUND ITSUU LAB | 2010-09-01 | — | — | CN | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189445-A1 | FIVE-MEMBERED HETEROCYCLIC COMPOUND | Research Foundation Itsuu Laboratory (JP) | 2010-05-26 | — | — | EP | disclosed |
| CN-101560272-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| CN-101560273-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213156-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | RXRA, RXRG, RXRB | KDM4E 2854/4885MAPT 4308/4885ALOX15 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.