Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 9/20 | 0.86 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.86 |
| ▸ | HTR2A | P28223 | 3/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069253 | 0.84 | SNCA (0.71) | MPOSLC6A4HTR2AHTR6HTR1A | |
| SCHEMBL25076892 | 0.84 | HTR2A (0.68) | MPOSLC6A4HTR2AHTR6 | |
| SCHEMBL830201 | 0.83 | MC5R (0.79) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5947615 | 0.82 | HTR2A (0.62) | MPOSLC6A4HTR2AHTR6HTR1A | |
| Hydrochloric Acid SCHEMBL11188453 | 0.82 | MC5R (0.77) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5947515 | 0.82 | MPO (0.60) | MPOSLC6A4HTR2AHTR6HTR1A | |
| SCHEMBL5947320 | 0.81 | HTR1A (0.61) | MPOSLC6A4HTR2AHDAC3HDAC4 | |
| SCHEMBL9827979 | 0.81 | HTR2A (0.64) | MPOSLC6A4HTR2A | |
| SCHEMBL948317 | 0.81 | HTR2A (1.00) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2405001 | 0.81 | MPO (1.00) | MPOSLC6A4HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | MPO 3915/4885SLC6A4 781/4885HTR2A 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.