Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | MC5R | P33032 | 2/20 | 0.52 |
| ▸ | MC3R | P41968 | 2/20 | 0.52 |
| ▸ | MC1R | Q01726 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947115 | 0.88 | KMT2A (0.59) | HTR2ASLC6A4MPOMC5RMC3R | |
| SCHEMBL5292952 | 0.85 | MC5R (0.66) | HTR2AMC5RMC3RMC1RCDK2 | |
| SCHEMBL27842093 | 0.82 | SLC6A4 (0.64) | SLC6A4 | |
| SCHEMBL25076892 | 0.81 | HTR2A (0.68) | HTR2ASLC6A4MPOKMT2A | |
| SCHEMBL2405136 | 0.81 | MPO (0.86) | HTR2ASLC6A4MPO | |
| SCHEMBL11069253 | 0.81 | SNCA (0.71) | HTR2ASLC6A4MPOMC5RMC3R | |
| SCHEMBL5947493 | 0.81 | HTR2A (0.56) | HTR2ASLC6A4MPOMC5RMC3R | |
| SCHEMBL4840057 | 0.81 | SLC6A4 (0.54) | SLC6A4MPO | |
| SCHEMBL5899817 | 0.80 | MEN1 (0.59) | SLC6A4SNCAKMT2A | |
| SCHEMBL830201 | 0.80 | MC5R (0.79) | HTR2AMC5RMC3RMC1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225726-B1 | INDOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4833153-A | VASOCONSTRICTORS, MIGRAINES | GLAXO GROUP LIMITED (GB) | 1989-05-23 | — | — | US | disclosed |
| EP-0225726-A1 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1987-06-16 | — | — | EP | disclosed |