SCHEMBL578968

SCHEMBL578968

O=C(O)CC(C(=O)O)=C(CC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.57
SRR Q9GZT4 1/20 0.57
FNTA P49354 2/20 0.56
FNTB P49356 2/20 0.56
TSHR P16473 4/20 0.41
KDM4E B2RXH2 2/20 0.41
EGLN1 Q9GZT9 3/20 0.38
LMNA P02545 3/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
OR51E2 Q9H255 3/20 0.35
FFAR3 O14843 1/20 0.35
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
MAPK1 P28482 1/20 0.35
SLC13A3 Q8WWT9 1/20 0.35
KDM5B Q9UGL1 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29127352 1.00 LDHA (0.57) LDHASRRFNTAFNTBTSHR
SCHEMBL1855287 1.00 LDHA (0.57) LDHASRRFNTAFNTBTSHR
SCHEMBL17706738 0.85 FFAR3 (0.47) LDHASRRFNTAFNTBTSHR
SCHEMBL17706779 0.85 FFAR3 (0.47) LDHASRRFNTAFNTBTSHR
SCHEMBL17706737 0.85 FFAR3 (0.47) LDHASRRFNTAFNTBTSHR
SCHEMBL27911245 0.83 LDHA (0.47) LDHASRRFNTAFNTBTSHR
SCHEMBL11192828 0.83 LDHA (0.47) LDHASRRFNTAFNTBTSHR
SCHEMBL290310 0.81 GRIK1 (0.44) LDHASRRFNTAFNTBTSHR
SCHEMBL12026335 0.81 FNTA (0.54) LDHASRRFNTAFNTBTSHR
SCHEMBL12045514 0.78 FNTA (0.46) LDHASRRFNTAFNTBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023184755-A1 SPECIAL HIGH-WATER-RESISTANCE BIO-BASED FORMALDEHYDE-FREE SETTING AGENT FOR MINERAL WOOL 江苏艾科赛特新材料有限公司 2023-10-05 WO claimed
CN-101484422-B Process for the preparation of sterically hindered nitroxyl ethers CIBA HOLDING INC 2012-07-11 CN claimed
EP-2035381-B1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS BASF SE (DE) 2010-12-29 EP claimed
CN-101484422-A Process for the preparation of sterically hindered nitroxyl ethers CIBA HOLDING INC (CH) 2009-07-15 CN claimed
EP-2035381-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS Ciba Holding Inc. (CH) 2009-03-18 EP claimed
WO-2008003602-A1 PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS CIBA HOLDING INC. (CH) 2008-01-10 WO claimed
CN-1882650-A Weather-resistant coloured polystyrene CIBA SC HOLDING AG (CH) 2006-12-20 CN claimed
CN-1823127-A Flame retardant polylactic acid CIBA SC HOLDING AG (CH) 2006-08-23 CN claimed
WO-2005090307-A1 A PROCESS FOR THE SYNTHESIS OF AMINE ETHERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-09-29 WO claimed
CN-1602334-A Flame retardant compositions CIBA SC HOLDING AG (CH) 2005-03-30 CN claimed
US-6403681-B2 STABILIZER FOR PLASTICS CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-11 US claimed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 US claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-09-06 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
CN-1261904-A Flame retardant compositions CIBA SC HOLDING AG (CH) 2000-08-02 CN claimed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP claimed
US-4831134-A N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1989-05-16 US claimed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 LDHA 1301/4885SRR 4539/4885FNTA 3894/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 LDHA 1301/4885SRR 4539/4885FNTA 3894/4885
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 LDHA 1301/4885SRR 4539/4885FNTA 3894/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 LDHA 1301/4885SRR 4539/4885FNTA 3894/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 LDHA 1301/4885SRR 4539/4885FNTA 3894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.