Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400587 | 0.72 | ORAI1 (0.42) | LMNA | |
| SCHEMBL24488 | 0.69 | ALDH1A1 (0.48) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL29391558 | 0.69 | ALDH1A1 (0.48) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL5601608 | 0.69 | ALDH1A1 (0.48) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL5571942 | 0.69 | CYP1A2 (0.48) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL22635045 | 0.69 | CYP1A2 (0.43) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL2405995 | 0.68 | ORAI1 (0.38) | — | |
| SCHEMBL7177934 | 0.67 | TRPV6 (0.52) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| Phenylboronic Acid SCHEMBL3985819 | 0.66 | ENPP2 (0.56) | ALDH1A1CYP1A2NR4A1NR4A2NR4A3 | |
| SCHEMBL2407734 | 0.66 | ORAI1 (0.42) | LMNAALDH1A1PPARGPPARASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | LMNA 3426/4885ALDH1A1 4540/4885CYP1A2 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.