SCHEMBL2405902

SCHEMBL2405902

O=C(O)N(Cc1cscn1)CC1CCN(c2cccc(-c3cc(F)cc(F)c3)n2)CC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 18/20 0.41
CNR1 P21554 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406060 0.87 DKK1 (0.42) FFAR4CNR1
SCHEMBL2405627 0.87 CNR1 (0.38) FFAR4CNR1
SCHEMBL2411198 0.87 PIM1 (0.36) FFAR4
SCHEMBL2406718 0.87 KMO (0.38) FFAR4CNR1
SCHEMBL2408111 0.86 PRKD1 (0.37) FFAR4CNR1
SCHEMBL2406555 0.86 KDM4E (0.39) FFAR4
SCHEMBL2404007 0.85 CPT2 (0.35) FFAR4
SCHEMBL2405635 0.85 PIM2 (0.36) FFAR4CNR1
SCHEMBL2407113 0.85 SMN1; SMN2 (0.44) FFAR4CNR1
SCHEMBL2411477 0.85 CNR1 (0.40) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912218-B2 Alkylthiazol carbamate derivatives, preparation thereof and therapeutic use thereof SANOFI (FR) 2014-12-16 US disclosed
US-20110212963-A1 ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2011-09-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212963-A1 ALKYLTHIAZOL CARBAMATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF MET, ALK, REL FFAR4 677/4885CNR1 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.