Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20782639 | 0.89 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL20692032 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22340256 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20692011 | 0.81 | ALDH1A1 (0.37) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22340218 | 0.71 | IMPDH2 (0.44) | — | |
| SCHEMBL22340207 | 0.69 | POLB (0.41) | — | |
| SCHEMBL14156808 | 0.67 | HPGD (0.57) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL26196385 | 0.66 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL20692222 | 0.66 | ALDH1A1 (0.32) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL18526197 | 0.64 | ALDH1A1 (0.50) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676279-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2021-12-01 | — | — | EP | disclosed |