Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | BAX | Q07812 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438291 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1HTTSMN1; SMN2FFAR1 | |
| SCHEMBL12890739 | 0.87 | ALDH1A1 (0.65) | KDM4EALDH1A1HTTSMN1; SMN2FFAR1 | |
| SCHEMBL23330026 | 0.82 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2FFAR1 | |
| SCHEMBL2954251 | 0.78 | CASR (0.60) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL15592744 | 0.77 | CYP1A2 (0.58) | KDM4EKMT2ASLC2A1MAPTPKM | |
| SCHEMBL23330025 | 0.77 | LMNA (0.57) | KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5112767 | 0.76 | LTA4H (0.55) | SMN1; SMN2FFAR1MEN1KMT2ALTA4H | |
| SCHEMBL30979265 | 0.76 | LTA4H (0.55) | SMN1; SMN2FFAR1MEN1KMT2ALTA4H | |
| SCHEMBL14438287 | 0.76 | LTA4H (0.50) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL6061334 | 0.75 | LTA4H (0.50) | FFAR1MEN1KMT2ALTA4HNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349581-B1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2021-12-01 | — | — | EP | disclosed |