Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24064580 | 0.84 | L3MBTL1 (0.52) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL24064585 | 0.83 | KMT2A (0.59) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL30556174 | 0.77 | L3MBTL1 (0.76) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL25009812 | 0.77 | L3MBTL1 (0.76) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL24064573 | 0.77 | L3MBTL1 (0.46) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL25332560 | 0.76 | L3MBTL1 (0.56) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL22861334 | 0.75 | HDAC8 (0.51) | L3MBTL1KMT2ACYP3A4SMN1; SMN2MEN1 | |
| Nicoboxil SCHEMBL288321 | 0.75 | L3MBTL1 (0.84) | L3MBTL1LMNAKMT2ASMN1; SMN2MEN1 | |
| Nicoboxil SCHEMBL29475326 | 0.75 | L3MBTL1 (0.84) | L3MBTL1LMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24064576 | 0.75 | L3MBTL1 (0.61) | L3MBTL1LMNAKMT2ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371446-A1 | SIRT1 ACTIVATING COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371446-A1 | SIRT1 ACTIVATING COMPOUNDS | SIRT1, SIRT2, SIRT3 | L3MBTL1 2991/4885LMNA 881/4885KMT2A 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.