Nicoboxil

Nicoboxil

SCHEMBL288321

CCCCOCCOC(=O)c1cccnc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.84
LMNA P02545 7/20 0.75
KMT2A Q03164 6/20 0.66
MAPT P10636 4/20 0.66
ALDH1A1 P00352 4/20 0.66
MEN1 O00255 2/20 0.66
HPGD P15428 1/20 0.66
CYP1A2 P05177 1/20 0.64
CYP2C9 P11712 1/20 0.64
TSHR P16473 1/20 0.64
CYP2C19 P33261 1/20 0.64
NFKB1 P19838 2/20 0.60
NFKB2 Q00653 2/20 0.60
RELA Q04206 2/20 0.60
NPC1 O15118 1/20 0.60
POLB P06746 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
TDP1 Q9NUW8 1/20 0.52
GAA P10253 1/20 0.50
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicoboxil SCHEMBL29475326 1.00 L3MBTL1 (0.84) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL25951682 0.95 LMNA (0.85) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL551716 0.91 L3MBTL1 (1.00) L3MBTL1LMNAKMT2AMAPTALDH1A1
Nicoboxil SCHEMBL14917483 0.91 TDP1 (0.70) L3MBTL1LMNAKMT2AMAPTALDH1A1
Hydrochloric Acid SCHEMBL5559952 0.90 L3MBTL1 (0.97) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL551811 0.87 LMNA (0.97) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL25329932 0.86 L3MBTL1 (0.62) L3MBTL1LMNAKMT2AMAPTALDH1A1
Sulfuric Acid SCHEMBL11419955 0.86 L3MBTL1 (0.89) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL4275232 0.86 LMNA (1.00) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL285214 0.86 LMNA (1.00) L3MBTL1LMNAKMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1044 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 US claimed
US-20250120907-A1 Transmucosal Drug Delivery System Masiz, John J. (US) 2025-04-17 US claimed
US-12246098-B2 Trans-epithelial membrane drug delivery system BioPhysics Pharma, Inc. (US) 2025-03-11 US claimed
US-20240216292-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2024-07-04 US claimed
US-20240108588-A1 Transdermal Drug Delivery System Masiz, John J. (US) 2024-04-04 US claimed
US-11865217-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2024-01-09 US claimed
EP-4106816-A1 TRANSMUCOSAL DRUG DELIVERY SYSTEM North Atlantic Holdings LLC (US) 2022-12-28 EP claimed
US-20220387343-A1 Transdermal Drug Delivery System Masiz, John J. (US) 2022-12-08 US claimed
US-11446257-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2022-09-20 US claimed
US-20080160070-A1 TRANSDERMAL VITAMIN B12 DELIVERY PATCH NEXAGEN USA LLC (US) 2008-07-03 US claimed
EP-1938789-A1 Improvement of the skin friendliness of hyperemizing agents Henkel AG & Co. KGaA (DE) 2008-07-02 EP claimed
EP-1890769-A1 HAIR TONIC INDENA S.p.A. (IT) 2008-02-27 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2006114188-A1 HAIR TONIC INDENA S.P.A. (IT) 2006-11-02 WO claimed
US-20060093656-A1 Warming patch HISAMITU PHARMACEUTICAL CO., INC. (JP) 2006-05-04 US claimed
EP-1568365-A1 WARM POULTICE HISAMITSU PHARMACEUTICAL CO. INC. (JP) 2005-08-31 EP claimed
WO-2005051365-A1 COMPOSITION AND DEVICE FOR FACILITATING VENIPUNCTURE MEDIS S.R.L. (IT) 2005-06-09 WO claimed
EP-0242827-B1 SURFACE SHAPED THERAPEUTIC SYSTEM, METHOD FOR ITS MANUFACTURE, AND ITS APPLICATION Lohmann GmbH & Co. KG (DE) 1991-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605345-B2 Transdermal drug delivery system FABP2, VEGFA, CUTA L3MBTL1 3949/4885LMNA 512/4885KMT2A 2706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.