Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715467 | 0.84 | LMNA (0.64) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL12771413 | 0.83 | LMNA (0.62) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL687664 | 0.80 | LOXL2 (0.67) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL27925916 | 0.79 | LMNA (0.57) | LMNACYP1A2CYP3A4MAOACA1 | |
| Hydrochloric Acid SCHEMBL367399 | 0.78 | LOXL2 (0.65) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL28245978 | 0.78 | LMNA (0.56) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL5831347 | 0.78 | LMNA (0.55) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL4643521 | 0.78 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL25533378 | 0.78 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOACA1 | |
| SCHEMBL128190 | 0.77 | CA1 (0.70) | LMNACYP1A2CYP3A4MAOACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |