Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | AGXT | P21549 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220041 | 0.87 | ALDH1A1 (0.34) | CA1CA2ALDH1A1MAPK1KMT2A | |
| SCHEMBL2219213 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1KMT2AGLANPSR1 | |
| SCHEMBL1503186 | 0.77 | MAPK1 (0.41) | CA1CA2ALDH1A1MAPK1KMT2A | |
| SCHEMBL5666626 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPK1KMT2ATSHR | |
| SCHEMBL1503248 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPK1KMT2AHDAC4HDAC6 | |
| SCHEMBL2220510 | 0.73 | UCHL1 (0.40) | ALDH1A1MAPK1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL1503282 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPK1KMT2AHDAC4HDAC6 | |
| SCHEMBL1503084 | 0.72 | SMPD1 (0.39) | ALDH1A1MAPK1KMT2AHDAC4HDAC6 | |
| SCHEMBL34413 | 0.64 | IDO1 (0.67) | CA1CA2ALDH1A1HTTSMN1; SMN2 | |
| Potassium SCHEMBL1477050 | 0.62 | IDO1 (0.64) | CA1CA2ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369688-A1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | MONTREAL HEART INSTITUTE (CA) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369688-A1 | METHODS OF TREATING ELEVATED PLASMA CHOLESTEROL | CETP, LDLR, APOB | CA1 2934/4885CA2 2129/4885ALDH1A1 568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.