Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240908 | 0.93 | TSHR (0.45) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL38661115 | 0.86 | TSHR (0.45) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL969754 | 0.84 | TSHR (0.42) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL30571184 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL4996914 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL7583697 | 0.81 | TSHR (0.56) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| Bromide SCHEMBL28268585 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL245065 | 0.80 | NPC1 (0.46) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL27811093 | 0.80 | TSHR (0.41) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL700968 | 0.79 | PDE4A (0.45) | SMN1; SMN2ALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859803-B2 | Process for production of ketomalonic acid compounds or hydrates thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2447243-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | ME1, CA6, ME3 | SMN1; SMN2 3843/4885ALDH1A1 1227/4885TSHR 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.