SCHEMBL24067355

SCHEMBL24067355

CC(C)c1ccc(CCC(C)c2ccc(Cl)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TAAR1 Q96RJ0 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ADRB2 P07550 1/20 0.42
KCNH2 Q12809 1/20 0.42
TMEM97 Q5BJF2 1/20 0.42
IDO1 P14902 2/20 0.41
AOC3 Q16853 1/20 0.40
DPP4 P27487 1/20 0.38
POLB P06746 1/20 0.38
C3AR1 Q16581 1/20 0.38
GAA P10253 1/20 0.38
TOP2A P11388 1/20 0.38
MAOB P27338 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24616595 0.86 ADRB2 (0.50) MEN1KMT2ARAB9ASMN1; SMN2SLC6A2
SCHEMBL29291900 0.85 ACHE (0.45) MEN1KMT2ATAAR1IDO1DPP4
SCHEMBL3359190 0.85 PPARG (0.44) MEN1KMT2ATAAR1SLC6A2SLC6A3
SCHEMBL24067501 0.84 KCNH2 (0.47) MEN1KMT2ARAB9ASMN1; SMN2TAAR1
SCHEMBL9587417 0.84 CYP19A1 (0.48) MEN1KMT2ATAAR1SLC6A2SLC6A3
SCHEMBL24997152 0.83 RAB9A (0.45) KMT2ARAB9ATAAR1IDO1ESR1
SCHEMBL6547394 0.78 CYP1A2 (0.46) MEN1KMT2ASMN1; SMN2TAAR1ADRB2
SCHEMBL14088916 0.77 MEN1 (0.51) MEN1KMT2ARAB9ASMN1; SMN2TAAR1
SCHEMBL436099 0.77 AOC3 (0.52) MEN1KMT2ATAAR1SLC6A2SLC6A3
SCHEMBL24106999 0.76 BCHE (0.39) RAB9ASMN1; SMN2TAAR1IDO1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210371441-A1 PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC USE CITY UNIVERSITY OF HONG KONG (HK) 2021-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210371441-A1 PLATINUM COMPLEX, ITS PREPARATION AND THERAPEUTIC USE IDH1, IDH2, IDH3A MEN1 2799/4885KMT2A 3377/4885RAB9A 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.