Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 3/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25769745 | 0.90 | NPC1 (0.46) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL8079864 | 0.89 | NPC1 (0.45) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL23071375 | 0.86 | RAB9A (0.39) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL17576277 | 0.84 | ALDH1A1 (0.41) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL6924910 | 0.83 | RAB9A (0.67) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL29724216 | 0.80 | ALDH1A1 (0.39) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL432261 | 0.80 | ALDH1A1 (0.39) | NPC1RAB9AGFERMAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL14915907 | 0.80 | ALDH1A1 (0.38) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL3366096 | 0.78 | ESR1 (0.62) | NPC1RAB9AGFERMAPTTP53 | |
| SCHEMBL3367118 | 0.76 | UTRN (0.57) | NPC1RAB9AGFERMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242976-A1 | FUNCTIONAL SKIN COATING POLYMER | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-12-02 | — | — | WO | disclosed |