Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 4/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724216 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL432261 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL23071375 | 0.85 | RAB9A (0.39) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL21586960 | 0.83 | MAPT (0.43) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL17576045 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL6927621 | 0.82 | RAB9A (0.43) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL25769745 | 0.81 | NPC1 (0.46) | ALDH1A1HSD17B10KDM4EMAPTPTPN5 | |
| SCHEMBL24068960 | 0.80 | NPC1 (0.50) | ALDH1A1HSD17B10KDM4EMAPTUSP2 | |
| SCHEMBL8079864 | 0.80 | NPC1 (0.45) | ALDH1A1HSD17B10KDM4EMAPTTSHR | |
| SCHEMBL23021160 | 0.79 | MAPT (0.41) | ALDH1A1HSD17B10KDM4EMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016939-B2 | Skin treatment methods and compositions for transdermal delivery of active agents | TOPIX PHARMACEUTICALS, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240108556-A1 | SCAR TREATMENT COMPOSITION | TOPIX PHARMACEUTICALS, INC. | 2024-04-04 | — | — | US | disclosed |
| US-20240075112-A1 | SCAR TREATMENT COMPOSITION | TOPIX PHARMACEUTICALS, INC. | 2024-03-07 | — | — | US | disclosed |
| US-20230190593-A1 | SKIN TREATMENT METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS | TOPIX PHARMACEUTICALS, INC. | 2023-06-22 | — | — | US | disclosed |
| US-11596584-B2 | Skin treatment methods and compositions for transdermal delivery of active agents | TOPIX PHARMACEUTICALS, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| US-20210401682-A1 | TOPICAL VITAMIN C COMPOSITION | TOPIX PHARMACEUTICALS, INC. | 2021-12-30 | — | — | US | disclosed |
| US-20210212908-A1 | SKIN TREATMENT METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS | TOPIX PHARMACEUTICALS, INC. | 2021-07-15 | — | — | US | disclosed |
| US-9987211-B2 | Sunless tanning compounds and compositions | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170000712-A1 | SUNLESS TANNING COMPOUNDS AND COMPOSITIONS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-01-05 | — | — | US | disclosed |
| WO-2015003095-A1 | SUNLESS TANNING COMPOUNDS AND COMPOSITIONS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2015-01-08 | — | — | WO | disclosed |
| US-8906351-B2 | 2,2′-furoin derivatives and use thereof to light skin | MERCK PATENT GMBH (DE) | 2014-12-09 | — | — | US | disclosed |
| US-20130272978-A1 | DIHYDROXYACETONE MONOETHERS | MERCK PATENT GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
| US-20130261175-A1 | 2-PYRONES | MERCK PATENT GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-20130164230-A1 | 2,2'-FUROIN DERIVATIVES AND USE THEREOF TO LIGHT SKIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-27 | — | — | US | disclosed |
| US-20130115178-A1 | TANNING ENHANCERS AND SELF-TANNING SUBSTANCES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130164230-A1 | 2,2'-FUROIN DERIVATIVES AND USE THEREOF TO LIGHT SKIN | TYR, ALDH1A2, MC1R | ALDH1A1 63/4885HSD17B10 439/4885KDM4E 4348/4885 |
| US-20170000712-A1 | SUNLESS TANNING COMPOUNDS AND COMPOSITIONS | TYR, SUN2, ERCC4 | ALDH1A1 1404/4885HSD17B10 2192/4885KDM4E 2412/4885 |
| US-20240108556-A1 | SCAR TREATMENT COMPOSITION | MMP1, MMP8, PLAT | ALDH1A1 296/4885HSD17B10 462/4885KDM4E 2616/4885 |
| US-20210401682-A1 | TOPICAL VITAMIN C COMPOSITION | TTPA, PROC, RBP4 | ALDH1A1 963/4885HSD17B10 2143/4885KDM4E 3248/4885 |
| US-20230190593-A1 | SKIN TREATMENT METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS | CUTA, MMP1, TYR | ALDH1A1 2153/4885HSD17B10 2361/4885KDM4E 4392/4885 |
| US-11596584-B2 | Skin treatment methods and compositions for transdermal delivery of active agents | CUTA, MMP1, TYR | ALDH1A1 2153/4885HSD17B10 2361/4885KDM4E 4392/4885 |
| US-20240075112-A1 | SCAR TREATMENT COMPOSITION | MMP1, MMP8, MMP2 | ALDH1A1 173/4885HSD17B10 405/4885KDM4E 1907/4885 |
| US-20130115178-A1 | TANNING ENHANCERS AND SELF-TANNING SUBSTANCES | DERA, ALDOA, GALE | ALDH1A1 5/4885HSD17B10 127/4885KDM4E 980/4885 |
| US-20130261175-A1 | 2-PYRONES | PYCR1, CYP17A1, CYP11B2 | ALDH1A1 658/4885HSD17B10 127/4885KDM4E 1753/4885 |
| US-20130272978-A1 | DIHYDROXYACETONE MONOETHERS | GNPAT, UGT1A7, UGT1A3 | ALDH1A1 27/4885HSD17B10 30/4885KDM4E 1761/4885 |
| US-12016939-B2 | Skin treatment methods and compositions for transdermal delivery of active agents | CUTA, MMP1, TYR | ALDH1A1 2153/4885HSD17B10 2361/4885KDM4E 4392/4885 |
| US-20210212908-A1 | SKIN TREATMENT METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS | CUTA, MMP1, TYR | ALDH1A1 2153/4885HSD17B10 2361/4885KDM4E 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.