Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079864 | 0.90 | NPC1 (0.45) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL24068960 | 0.90 | NPC1 (0.50) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL17576277 | 0.85 | ALDH1A1 (0.41) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL29724216 | 0.81 | ALDH1A1 (0.39) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL432261 | 0.81 | ALDH1A1 (0.39) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL14915907 | 0.81 | ALDH1A1 (0.38) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL3366096 | 0.79 | ESR1 (0.62) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL6924910 | 0.79 | RAB9A (0.67) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL23071375 | 0.78 | RAB9A (0.39) | NPC1RAB9AGFERKDM4EALDH1A1 | |
| SCHEMBL3367118 | 0.77 | UTRN (0.57) | NPC1RAB9AGFERKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | THE JOHNS HOPKINS UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | CUTA, PUF60, SUN2 | NPC1 3697/4885RAB9A 2816/4885GFER 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.