Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 15/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073698 | 0.85 | STAT3 (0.52) | STAT3POLQNPC1MITFALDH1A1 | |
| SCHEMBL24073701 | 0.82 | POLQ (0.47) | STAT3POLQNPC1MITFALDH1A1 | |
| SCHEMBL24072284 | 0.81 | ADORA2A (0.44) | STAT3NPC1MITFALDH1A1LMNA | |
| SCHEMBL25063047 | 0.81 | STAT3 (0.64) | STAT3NPC1ALDH1A1LMNARAB9A | |
| SCHEMBL24072273 | 0.81 | TP53 (0.48) | POLQNPC1MITFALDH1A1LMNA | |
| SCHEMBL24072282 | 0.81 | CCNE1 (0.41) | STAT3NPC1MITFALDH1A1LMNA | |
| SCHEMBL24072346 | 0.81 | STAT3 (0.41) | STAT3NPC1MITFALDH1A1LMNA | |
| SCHEMBL24074132 | 0.79 | ALDH1A1 (0.54) | STAT3NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24072268 | 0.79 | MAPK14 (0.47) | STAT3NPC1MITFALDH1A1LMNA | |
| SCHEMBL24072313 | 0.77 | STAT3 (0.52) | STAT3POLQNPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |