Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.43 |
| ▸ | CDK11A | Q9UQ88 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072281 | 0.88 | LRRK2 (0.48) | RAB9AKDM4EALDH1A1GLAMAPT | |
| SCHEMBL24072279 | 0.86 | MAPK14 (0.49) | MAPK14RAB9ANPC1LCKL3MBTL1 | |
| SCHEMBL24074689 | 0.85 | MAPK14 (0.48) | MAPK14RAB9ANPC1LCKL3MBTL1 | |
| SCHEMBL25063113 | 0.84 | STAT3 (0.58) | MAPK14RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL24073698 | 0.79 | STAT3 (0.52) | RAB9ANPC1KDM4EALDH1A1GLA | |
| SCHEMBL24073701 | 0.77 | POLQ (0.47) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL24072284 | 0.76 | ADORA2A (0.44) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL24072282 | 0.75 | CCNE1 (0.41) | MAPK14RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL24072346 | 0.75 | STAT3 (0.41) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL24072271 | 0.75 | ITK (0.43) | RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |