Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072300 | 0.86 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24072437 | 0.85 | MAPK14 (0.44) | ALDH1A1RAB9ASMN1; SMN2KMT2ATP53 | |
| SCHEMBL25063314 | 0.84 | STAT3 (0.65) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24074074 | 0.78 | RAB9A (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL25063117 | 0.77 | STAT3 (0.65) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21579699 | 0.72 | TOP1 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL24072758 | 0.72 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24072436 | 0.71 | POLQ (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL23348163 | 0.70 | NPC1 (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24074435 | 0.70 | STAT3 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |