Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | CBFB | Q13951 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075401 | 0.88 | NPBWR1 (0.58) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL24075398 | 0.86 | DGAT1 (0.66) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL8772505 | 0.83 | SIRT2 (0.59) | ALDH1A1HPGDHSD17B10SIRT2SIRT1 | |
| SCHEMBL24075393 | 0.83 | CHEK2 (0.53) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL1663224 | 0.81 | MEN1 (0.67) | ALDH1A1HPGDHSD17B10KDM4ECYP3A4 | |
| SCHEMBL1663221 | 0.81 | PARP1 (0.52) | ALDH1A1HPGDHSD17B10KDM4ECYP3A4 | |
| SCHEMBL24075347 | 0.80 | DGAT1 (0.60) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL16205099 | 0.80 | ACHE (0.68) | ALDH1A1HPGDHSD17B10KDM4ESIRT2 | |
| SCHEMBL19137959 | 0.80 | NPBWR1 (0.55) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 | |
| SCHEMBL28086854 | 0.79 | TCF4 (0.54) | ALDH1A1HPGDHSD17B10KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2021242790-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192626-A1 | NOVEL SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHOD OF USE THEREOF | EPHX1, EPHX2, NCEH1 | ALDH1A1 588/4885HPGD 60/4885HSD17B10 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.