Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 11/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074938 | 0.89 | PTGES (0.57) | HIF1AEPAS1MAOBPTGESALOX5 | |
| SCHEMBL24075655 | 0.85 | MEN1 (0.49) | HIF1AEPAS1MEN1KMT2AMAOB | |
| SCHEMBL31576814 | 0.84 | HIF1A (0.54) | HIF1AEPAS1PTGESALOX5 | |
| SCHEMBL24075664 | 0.84 | HIF1A (0.54) | HIF1AEPAS1PTGESALOX5 | |
| SCHEMBL31580515 | 0.81 | MEN1 (0.49) | HIF1AEPAS1MEN1KMT2AMAOB | |
| SCHEMBL15360775 | 0.77 | PTGES (0.56) | MEN1KMT2AMAOBPTGESALOX5 | |
| SCHEMBL15361077 | 0.76 | MAOB (0.49) | HIF1AEPAS1MEN1KMT2ALMNA | |
| Achyrofuran SCHEMBL505137 | 0.75 | HIF1A (0.57) | HIF1AEPAS1MEN1KMT2ALMNA | |
| Achyrofuran SCHEMBL29375603 | 0.75 | HIF1A (0.57) | HIF1AEPAS1MEN1KMT2ALMNA | |
| SCHEMBL6125217 | 0.75 | HIF1A (0.55) | HIF1AEPAS1MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104281-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-05-22 | — | — | WO | disclosed |
| EP-4556004-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | Centre National de la Recherche Scientifique (FR) | 2025-05-21 | — | — | EP | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-09 | — | — | US | disclosed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | HIF1A 1162/4885EPAS1 1446/4885MEN1 2952/4885 |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | HIF1A 1162/4885EPAS1 1446/4885MEN1 2952/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | HIF1A 1162/4885EPAS1 1446/4885MEN1 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.