Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075664 | 1.00 | HIF1A (0.54) | HIF1AEPAS1PTGESALOX5PTGS1 | |
| SCHEMBL24075662 | 0.89 | PTGES (0.72) | PTGESALOX5PTGS1PTGS2CTSL | |
| SCHEMBL24075565 | 0.87 | FFAR1 (0.59) | HIF1AEPAS1PTGESALOX5PTGS1 | |
| SCHEMBL31576809 | 0.87 | FFAR1 (0.59) | HIF1AEPAS1PTGESALOX5PTGS1 | |
| SCHEMBL24075656 | 0.84 | HIF1A (0.56) | HIF1AEPAS1PTGESALOX5 | |
| SCHEMBL31576819 | 0.81 | ALOX5 (0.76) | PTGESALOX5PTGS1PTGS2SMPD1 | |
| SCHEMBL9578229 | 0.81 | ALOX5 (0.76) | PTGESALOX5PTGS1PTGS2SMPD1 | |
| SCHEMBL30100945 | 0.80 | PTGS1 (0.58) | PTGESALOX5PTGS1PTGS2SMPD1 | |
| SCHEMBL30100963 | 0.79 | FFAR1 (0.64) | HIF1AEPAS1PTGESALOX5PTGS1 | |
| SCHEMBL30550437 | 0.77 | FBP1 (0.56) | HIF1AEPAS1PTGESALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104281-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2025-05-22 | — | — | WO | disclosed |
| EP-4556004-A1 | HOP DERIVED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES CAUSED BY CORONAVIRUSES | Centre National de la Recherche Scientifique (FR) | 2025-05-21 | — | — | EP | disclosed |