Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23587955 | 0.87 | RECQL (0.50) | ALDH1A1RECQLGAAPAOXFAAH | |
| SCHEMBL5285987 | 0.83 | RECQL (0.38) | ALDH1A1RECQLLMNAGAATPSAB1 | |
| SCHEMBL16217889 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RECQLLMNASLC15A2GAA | |
| SCHEMBL7668119 | 0.81 | MGAM (0.35) | ALDH1A1RECQLLMNAGAAPHF8 | |
| SCHEMBL9870186 | 0.79 | PHF8 (0.52) | ALDH1A1RECQLLMNAPHF8KDM2A | |
| SCHEMBL7771322 | 0.79 | CTSD (0.52) | ALDH1A1RECQLLMNAGAAFAAH | |
| SCHEMBL25917430 | 0.78 | RECQL (0.54) | ALDH1A1RECQLGAATPSAB1FAAH | |
| SCHEMBL19155815 | 0.78 | RECQL (0.46) | ALDH1A1RECQLLMNASLC15A2GAA | |
| SCHEMBL7997866 | 0.77 | ALDH1A1 (0.46) | ALDH1A1RECQLLMNASLC15A2GAA | |
| SCHEMBL31261082 | 0.76 | MAOA (0.40) | ALDH1A1RECQLLMNAGAATPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210373012-A1 | METHODS FOR DETECTING HIS-TAGGED PROTEINS USING NTA PROBES AND POLYACRYLAMIDE GEL ELECTROPHORESIS | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2021-12-02 | — | — | US | disclosed |