Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.31 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420273 | 0.92 | HTR6 (0.36) | PTGDR2CCKARHTR6 | |
| SCHEMBL2411936 | 0.90 | EPHX2 (0.33) | PTGDR2CCKAR | |
| SCHEMBL2415890 | 0.90 | GAA (0.32) | PTGDR2CCKAR | |
| SCHEMBL2409039 | 0.90 | RXFP1 (0.33) | PTGDR2CCKAR | |
| SCHEMBL2411542 | 0.90 | MET (0.41) | METPTGDR2CHRM5HTR6 | |
| SCHEMBL2410118 | 0.89 | PPME1 (0.35) | PTGDR2HTR6 | |
| SCHEMBL2411045 | 0.88 | PTGER2 (0.33) | PTGDR2HTR6 | |
| SCHEMBL2408493 | 0.88 | GAA (0.30) | PTGDR2 | |
| SCHEMBL2409445 | 0.87 | ESR1 (0.39) | PTGDR2CCKARHTR6 | |
| SCHEMBL5003157 | 0.87 | MET (0.41) | METPTGDR2CCKARPIP4K2APIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |