Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076242 | 0.88 | CYP2C19 (0.58) | ALOX15AKR1B1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24076920 | 0.83 | ALOX15 (0.70) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL24076925 | 0.83 | ALOX15 (0.70) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL30168552 | 0.82 | ALOX15 (0.68) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL24077161 | 0.82 | ALOX15 (0.68) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL30168576 | 0.81 | NLRP3 (0.47) | ALOX15AKR1B1ALDH1A1GAAPKM | |
| SCHEMBL24077328 | 0.81 | NLRP3 (0.47) | ALOX15AKR1B1ALDH1A1GAAPKM | |
| SCHEMBL24077130 | 0.80 | ALOX15 (0.65) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL24076918 | 0.80 | ALOX15 (0.65) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 | |
| SCHEMBL24076967 | 0.79 | ALOX15 (1.00) | ALOX15AKR1B1TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | ALOX15 289/4885AKR1B1 162/4885TSHR 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.