Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 17/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24077007 | 0.85 | NLRP3 (0.59) | NLRP3KMT2AAKR1B1 | |
| SCHEMBL24077213 | 0.85 | NLRP3 (0.60) | NLRP3AKR1B1MAPT | |
| SCHEMBL30168573 | 0.85 | NLRP3 (0.60) | NLRP3AKR1B1MAPT | |
| SCHEMBL24077227 | 0.83 | NLRP3 (0.55) | NLRP3AKR1B1 | |
| SCHEMBL24076982 | 0.83 | NLRP3 (0.55) | NLRP3AKR1B1 | |
| SCHEMBL24834877 | 0.83 | NLRP3 (0.53) | NLRP3 | |
| SCHEMBL24077195 | 0.81 | NLRP3 (0.53) | NLRP3AKR1B1 | |
| SCHEMBL24076990 | 0.81 | NLRP3 (0.58) | NLRP3 | |
| SCHEMBL24077286 | 0.81 | NLRP3 (0.56) | NLRP3MAPT | |
| SCHEMBL24076985 | 0.80 | NLRP3 (0.60) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | NLRP3 1/4885MEN1 1965/4885KMT2A 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.