Scoparone

Scoparone

SCHEMBL240777

COc1cc2ccc(=O)oc2cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 1.00
CA9 Q16790 11/20 0.77
CA12 O43570 10/20 0.77
CA1 P00915 8/20 0.77
CA7 P43166 7/20 0.77
KDM4E B2RXH2 7/20 0.77
CA13 Q8N1Q1 6/20 0.77
ALDH1A1 P00352 6/20 0.77
HPGD P15428 6/20 0.77
HSD17B10 Q99714 6/20 0.77
AKR1B1 P15121 4/20 0.77
GLA P06280 4/20 0.77
MEN1 O00255 3/20 0.77
CASP1 P29466 3/20 0.77
CASP7 P55210 3/20 0.77
KMT2A Q03164 3/20 0.77
CYP1A2 P05177 2/20 0.77
GAA P10253 2/20 0.77
HIF1A Q16665 2/20 0.77
ERAP1 Q9NZ08 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Scoparone SCHEMBL29714063 1.00 MCL1 (1.00) MCL1CA9CA12CA1CA7
Scoparone SCHEMBL27678756 0.96 MCL1 (0.93) MCL1CA9CA12CA1CA7
SCHEMBL15842691 0.90 MCL1 (0.81) MCL1CA9CA12CA1CA7
Scoparone SCHEMBL28143782 0.90 MCL1 (0.81) MCL1CA9CA12CA1CA7
Scoparone SCHEMBL1259077 0.90 MCL1 (0.81) MCL1CA9CA12CA1CA7
SCHEMBL15842882 0.88 MCL1 (0.78) MCL1CA9CA12CA1CA7
SCHEMBL6703874 0.88 MCL1 (0.78) MCL1CA9CA12CA1CA7
Scopoletin SCHEMBL29712325 0.88 CA9 (1.00) MCL1CA9CA12CA1CA7
Scopoletin SCHEMBL147702 0.88 CA9 (1.00) MCL1CA9CA12CA1CA7
Scopoletin SCHEMBL21114360 0.88 CA9 (1.00) MCL1CA9CA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS INTERNATIONAL N&H DENMARK APS (DK) 2026-05-28 US claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
EP-4719404-A2 METHODS FOR ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF BEVEMIPRETIDE Stealth BioTherapeutics Inc. (US) 2026-04-08 EP claimed
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS STEALTH BIOTHERAPEUTICS INC. (US) 2026-02-19 US claimed
CN-120137927-A Coumarin oxymethyl transferase derived from herba Artemisiae Scopariae, carrier and application thereof 西南大学 2025-06-13 CN claimed
EP-4565195-A1 LIGHT-MODULATING COSMETIC COMPOSITIONS AND USES THEREOF Lucas Meyer Cosmetics (FR) 2025-06-11 EP claimed
CN-118415901-B Composition with water-oil coherent effect and preparation method and application thereof 太和康美(北京)中医研究院有限公司 2025-05-02 CN claimed
CN-116064607-B Method for preparing scoparone by high-activity O-methyltransferase gene 西南大学 2025-04-18 CN claimed
EP-4533059-A1 ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF ELAMIPRETIDE Stealth BioTherapeutics Inc. (US) 2025-04-09 EP claimed
US-4906471-A Pharmaceutical composition for the reducing both hyperlipidemia and platelet-aggregation (PHP) LIU YAGUANG (US) 1990-03-06 US claimed
US-4851195-A FOR DETERMINING LIQUID PARTIAL PRESSURE; CONTAINING AN ABSORBER, A FLUORESCER AND BICARBONATE PFIZER HOSPITAL PRODUCTS GROUP, INC. (US) 1989-07-25 US claimed
US-4842859-A PLANT EXTRACTS; SCOPARONE OR AUROPTEN, CURCUMIN, FERULIC ACID, FLAVANOIDS AND FISH OIL; NONTOXIC LIU YAGUANG (US) 1989-06-27 US claimed
US-4812532-A GLASS OR SILICA GEL SUPPORT, ANALYZING AMINES BIO-AFFINITY SYSTEMS, INC. (US) 1989-03-14 US claimed
US-4812362-A POLYMERIC COATING ON GLASS OR SILICA GEL, CHROMATOGRAPHY BIO-AFFINITY SYSTEMS, INC. (US) 1989-03-14 US claimed
WO-1989001406-A1 SOLID PHASE N-HYDROXYSUCCINIMIDE REAGENTS AND USE OF SAME BIO-AFFINITY SYSTEMS, INC. (US) 1989-02-23 WO claimed
EP-0304248-A2 Carbon dioxide sensor Pfizer Hospital Products Group, Inc. (US) 1989-02-22 EP claimed
EP-0283116-A2 Sensor system SHILEY INCORPORATED (US) 1988-09-21 EP claimed
EP-0257887-A2 Ophthalmic compositions HOUSTON BIOTECHNOLOGY INCORPORATED (US) 1988-03-02 EP claimed
US-4334020-A Method of producing L-glutamic acid by fermentation AJINOMOTO COMPANY INCORPORATED (JP) 1982-06-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048096-A1 METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS NR2E3, ALDH1A2, PDE6D MCL1 4768/4885CA9 349/4885CA12 2963/4885
US-20260146992-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS FABP2, AADAT, HNMT MCL1 4512/4885CA9 1400/4885CA12 1961/4885
US-20260146298-A1 INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS FABP2, SI, CSTB MCL1 4061/4885CA9 675/4885CA12 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.