SCHEMBL24079384

SCHEMBL24079384

C=CO/C(=C\C)c1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
HTT P42858 3/20 0.39
NPSR1 Q6W5P4 3/20 0.39
LMNA P02545 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
PKM P14618 2/20 0.39
ATM Q13315 2/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NLRP1 Q9C000 1/20 0.39
NTSR1 P30989 1/20 0.39
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
GAA P10253 1/20 0.34
MAPT P10636 3/20 0.34
THRB P10828 1/20 0.34
SRD5A2 P31213 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22022955 0.82 CES2 (0.37) HTTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL21341267 0.79 TPMT (0.37) ALDH1A1MEN1KMT2A
SCHEMBL21341454 0.79 PLK1 (0.39) ALDH1A1HTTNPSR1LMNASMN1; SMN2
SCHEMBL25078684 0.77 PARP1 (0.43) ALDH1A1TDP1SMN1; SMN2HPGDMEN1
SCHEMBL2092522 0.76 TDP1 (0.52) ALDH1A1HTTNPSR1LMNATDP1
SCHEMBL13838540 0.76 TDP1 (0.52) ALDH1A1HTTNPSR1LMNATDP1
SCHEMBL714705 0.75 TDP1 (0.57) ALDH1A1HTTNPSR1LMNATDP1
SCHEMBL7767010 0.75 ALDH1A1 (0.39) ALDH1A1HTTNPSR1LMNATDP1
SCHEMBL14282871 0.72 LMNA (0.48) ALDH1A1HTTNPSR1LMNATDP1
SCHEMBL13811104 0.71 ALDH1A1 (0.39) ALDH1A1HTTNPSR1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11193065-B2 Liquid crystal composition, method of producing the same, and retardation film constituted from the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-12-07 US disclosed