Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092522 | 1.00 | TDP1 (0.52) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15801061 | 0.81 | ESR1 (0.52) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL2091071 | 0.79 | CA1 (0.54) | ALDH1A1MAPTKDM4ESMN1; SMN2HPGD | |
| SCHEMBL2096972 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL342989 | 0.78 | TSHR (0.50) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2777335 | 0.78 | TSHR (0.50) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8588497 | 0.78 | TSHR (0.50) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14282871 | 0.77 | LMNA (0.48) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28732348 | 0.77 | TDP1 (0.59) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL24079384 | 0.76 | ALDH1A1 (0.39) | TDP1ALDH1A1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120289716-A1 | METHOD FOR HIGH-SPEED FLUOROMETHYLATION AND PROCESS FOR PREPARATION OF PET TRACER USING SAME | RIKEN (JP) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289716-A1 | METHOD FOR HIGH-SPEED FLUOROMETHYLATION AND PROCESS FOR PREPARATION OF PET TRACER USING SAME | FCGR1A, FCGR3B, FCGR2A | TDP1 3579/4885ALDH1A1 4752/4885MAPT 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.