SCHEMBL240809

SCHEMBL240809

Nc1cccc(F)c1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 2/20 0.42
NPY1R P25929 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
USP2 O75604 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MGMT P16455 1/20 0.39
TSHR P16473 2/20 0.38
GPR35 Q9HC97 1/20 0.38
PDE7A Q13946 1/20 0.38
LMNA P02545 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29795544 1.00 ALDH1A1 (0.43) ALDH1A1TDP1SMN1; SMN2MAPTNPY1R
SCHEMBL240574 0.84 TDP1 (0.52) ALDH1A1TDP1SMN1; SMN2MAPTMGMT
SCHEMBL3390153 0.84 TDP1 (0.52) ALDH1A1TDP1SMN1; SMN2MAPTMEN1
SCHEMBL11551067 0.84 TDP1 (0.52) ALDH1A1TDP1SMN1; SMN2MAPTMEN1
SCHEMBL15861931 0.83 SMN1; SMN2 (0.40) ALDH1A1TDP1SMN1; SMN2MAPTNPY1R
SCHEMBL11901676 0.83 ALDH1A1 (0.45) ALDH1A1TDP1SMN1; SMN2MAPTNPY1R
Hydrochloric Acid SCHEMBL5914596 0.82 TDP1 (0.50) ALDH1A1TDP1SMN1; SMN2MAPTMEN1
SCHEMBL8066551 0.81 MEN1 (0.44) ALDH1A1TDP1SMN1; SMN2MAPTMEN1
SCHEMBL2843518 0.77 TDP1 (0.45) ALDH1A1TDP1SMN1; SMN2MAPTNPY1R
SCHEMBL17934 0.77 TSHR (0.59) ALDH1A1TDP1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 CN claimed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 CN claimed
EP-0743848-B1 2-FLUORO-6-NITROANILINES HENKEL KGAA (DE) 2000-11-08 EP claimed
US-20260144881-A1 HPK1 TARGETING COMPOUNDS AND USES THEREOF ARVINAS OPERATIONS, INC. (US) 2026-05-28 US disclosed
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF UNIV DE MONTREAL (CA) 2026-05-21 US disclosed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
CN-117177975-B Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2026-05-19 CN disclosed
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS MIRATI THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-12589156-B2 Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) ARVINAS OPERATIONS, INC. (US) 2026-03-31 US disclosed
EP-4665456-A1 BENZIMIDAZOLE AND BENZIMIDAZOLONE BASED PROTAC COMPOUNDS FOR THE TARGETED DEGRADATION OF LEUCINE RICH REPEAT KINASE 2 (LRRK2) Arvinas Operations, Inc. (US) 2025-12-24 EP disclosed
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease UNIVERSITE DE MONTREAL (CA) 2025-11-25 US disclosed
CN-100477037-C Electrolytic capacitor and electrolyte for driving electrolytic capacitor RUBYCON CORP (JP) 2009-04-08 CN disclosed
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 CN disclosed
WO-2008021851-A2 NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS SMITHKLINE BEECHAM CORPORATION (US) 2008-02-21 WO disclosed
WO-2008021851-A2 NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS SMITHKLINE BEECHAM CORPORATION (US) 2008-02-21 WO disclosed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 CN disclosed
CN-1494723-A Electrolytic capacitor and electrolyte for driving electrolytic capacitor 如碧空株式会社 2004-05-05 CN disclosed
CN-1333770-A Novel Bicyclic Compounds BASLIER PHARMACEUTICAL AG (CH) 2002-01-30 CN disclosed
US-RE30798-E BY REACTING 4-FLUORO-3-NITROANILINES WITH AMMONIA OR A PRIMARY OR SECONDARY AMINE CLAIROL INCORPORATED (US) 1981-11-17 US disclosed
US-3944612-A HAIR DYE INTERMEDIATES CLAIROL INCORPORATED (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144881-A1 HPK1 TARGETING COMPOUNDS AND USES THEREOF SGK1, PBK, SGK3 ALDH1A1 4640/4885TDP1 2979/4885SMN1; SMN2 4675/4885
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS PRMT5, PRMT1, PRMT3 ALDH1A1 4159/4885TDP1 963/4885SMN1; SMN2 2602/4885
US-20260137697-A1 THIAZOLO[5,4-D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF NRAS, KRAS, BRAF ALDH1A1 2369/4885TDP1 1807/4885SMN1; SMN2 3532/4885
US-12589156-B2 Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (LRRK2) LRRK2, SNCA, PARK7 ALDH1A1 3225/4885TDP1 3310/4885SMN1; SMN2 89/4885
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, DPYD ALDH1A1 1619/4885TDP1 489/4885SMN1; SMN2 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.